Specification: chlorogenic acid 5-98%（10% 25% 30% 50% 90%） (HPLC)
Molecular formula: C16H18O9 CAS No: 327-97-9
Einecs No:206-325-6
Molecular weight: 354.31
Solubility: Good solubility in water
Melting point:205-209
Appearance: Fine crystal powder
Color: White （chlorogenic acid 98% 99%）
Specific Rotation [α]: -36° (c=1,H2O)
Density:1.28 g/cm3
Melting point:207 - 209 °C
Structure :
Chlorogenic acid Chlorogenic acid is a phenolic natural product isolated from the
leaves and fruits of dicotyledonous plants,including the coffee bean. The ester of caffeic
acid with quinic acid,is one of the most abundant polyphenols in the human diet with coffee,
fruits and vegetables as its major sources. Its antioxidantand anticarcinogenic properties have
been well established in animal studies.lorogenic Acid
Function:
a) Can be used as anti-infectious active ingredient
b) Has wide anti-virus, anti-bacteria effects
c) Has relatively lower toxicity and side-effects
d) Has obvious anti-infectious effects.
e) Due to its obvious anti-infectious effects, it not only can be used in pharmaceutical field
but also can be used widely in many other fields like food, feed additives and cosmetics
f) Chlorogenic Acid—Best ingredients for cosmetic product
I. Strong Anti-oxidant ability
III.Very stable at normal temperature
V. No hypersusceptibility
VI.100% natural
g)Chlorogenic acid and caffeic acid are antioxidants in vitro and might therefore contribute to
the prevention of Type 2 Diabetes Mellitus and cardiovascular disease. h)Chlorogenic acid has
been proven in animal studies in vitro to inhibit the hydrolysis of the glucose-6-phosphate
enzyme in an irreversible fashion.The studies also confirmed a reduction in blood glucose
evels and an increase in the intrahepatic concentrations of glucose-6-phosphate and of glycogen.
Description of chlorogenic acid:
a) Has a wide range of biological effects, from insect resistance to human health
b) An important factor in plant metabolism
c) An antioxidant and has anti-fungi effectivity,stronger than the antibacterial
effectivity
d) An ester of caffeic acid and quinic acid, a major phenolic compound in coffee,
the daily intake of coffee drinkers is 0.05-0.1g
e)Strong antioxidants in vitro and could therefore be contribute to the prevention of disease
caused by free radicals Chlorogenic acid, an ester of caffeic acid and quinic acid, is a major
phenolic compound in coffee, but is also found widespread in plants and can be isolated from the
leaves and fruit . This compound, long known as an antioxidant, also slows the release of glucose
into the bloodstream after a meal.
f) Structurally, chlorogenic acid (CGA) is the ester formed between caffeic acid and (L)-quinic
aicd(1L-1(OH),3,4/5-tetrahydroxycyclohexanecarboxylic acid). Isomerisation of the quinic acid
in position 3, (3-CQA),4 (4-CQA) and 5 (5-CQA). Isomerisation at position 1 has not yet been
reported. Isomers of chlorogenic acid are found in potatoes. They are 4-O-caffeoylquinic acid
(crypto-chlorogenic acid), 5-O-caffeoylquinic acid (neo-chlorogenic acid), 3,4-dicaffeoylquinic
acid and 3,5-dicaffeoylquinic acid.
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